Setback

noun

1. An obstacle, delay, disadvantage, blow (an adverse event which retards or prevents progress towards a desired outcome)

   "After some initial setbacks, the expedition went safely on its way."

2. The required distance between a structure and a road.
3. A step-like recession in a wall.

   "Setbacks were initially used for structural reasons, but now are often mandated by land use codes."

4. An offset to the temperature setting of a thermostat to cover a period when more or less heating is required than usual.
5. (possibly obsolete) A backset; a countercurrent; an eddy.